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印度JRF实验室
简 介


JRF是一家印度OECD GLP实验室,誉鸿咨询自2012年11月开始作为其国内代理合作。

JRF是一家独立实验机构,建立于1977年,有42年历史.

JRF可提供毒理学,环境毒理,分析化学,环境行为和代谢,及法规知道等方面的服务.

JRF产品覆盖农化产品,医药产品,生物制品,食品和特殊化学品.

JRF实验面积有15,000平方米.

JRF人员总计有250人, 其中技术人员有150人.

 
机 构 组 成
JRF GLOBAL CONTENTS:
1. JRF INDIA
COMPREHENSIVE TOXICOLOGY,
PRODUCT CHEMISTRY,
E-FATE

2. JRF AMERICA
E-FATE,
EFFICACY,
EXPOSURE,
RESIDUE,
CHEMISTRY

3. GC LABORATORIES
PRODUCT,

4. JRF INTERNATIONAL
REGULATORY CONSULTANCY
REACH,
5-B,
EFFICACY TRIALS,
RESIDUE TRIALS,
RESIDUE,
CHEMISTRY

JRF集团包含:
1. 印度JRF实验室
综合毒理学,
产品化学,
环境行为

2. 美国JRF实验室
环境行为,
药效实验,
暴露实验,
残留实验,
化学分析

3. 英国JRF实验室
产品

4. 英国JRF咨询服务公司
法规咨询,
REACH,
5批次,
药效试验,
残留实验,
残留,
化学分析

检 测 产 品 范 围
1. AGRICULTURAL CHEMICALS
2. FOODS
3. PHARMACEUTICALS


1. 农化产品
2. 食品
3. 医药产品
印 度 JRF 服 务 范 围
1. Comprehensive Toxicology
1.1 Acute,
1.2 Chronic and Developmental and Genetic Toxicity,
1.3 EDSP

2. Product Chemistry
2.1 5 BA
2.2 Phys-chem
2.3 MD-MV

3. E-fate & Ecotox

4. Regulatory Consultancy & REACH
1. 综合毒理
1.1 急性
1.2 慢性, 发育和遗传毒性
1.3 EDSP

2. 产品化学
2.1 5批次
2.2 理化
2.3 分析方法建立和验证

3. 环境行为和环境毒性

4. 登记咨询和REACH
 

毒 理 学 实 验

 
  TEST METHOD TEST

1.    ACUTE STUDIES

  420 Acute Oral Toxicity, Mouse / Rat
  423 Acute Oral Toxicity, Mouse / Rat
  425 Acute Oral Toxicity, Mouse / Rat
  402 Acute Dermal Toxicity, Rat
  403 Acute Inhalation Toxicity, Rat
  404 Acute Dermal Irritation / Corrosion, Rabbit
  405 Acute Eye Irritation / Corrosion, Rabbit
  406 Skin Sensitisation - Guinea pig (Buehler Test)

2.    SUBCHRONIC STUDIES

  407 Repeated Dose Oral Toxicity - Rodent : 28 - Day
  408 Subchronic Oral Toxicity - Rodent :  90 - Day
  Chronic Toxicity Study – Rodent : 180 - Day
  410 Repeated Dose Dermal Toxicity : 21 / 28 - Day
  411 Subchronic Dermal Toxicity :  90 – Day
  414 Teratogenicity, Rat
  Teratogenicity, Rabbit
  415 One - Generation Reproduction Toxicity Study
  416 Two - Generation Reproduction Toxicity  Study
  418 Acute Delayed Neurotoxicity of Organophosphorous Substances
  422 Reproduction / Developmental Toxicity Screening Test
  451 Carcinogenicity Study - Mouse
  Carcinogenicity Study - Rat
  452 Chronic Toxicity Study – Rodent (1 Year)
  453 Combined Chronic Toxicity / Carcinogenicity Study – Rodent
3.    GENETIC TOXICOLOGY
  471 Salmonella typhimurium, Reverse Mutation Assay (Ames Test)
  473 In vitro Mammalian Cytogenetic Test
  474 Micronucleus Test
  475 In vivo Mammalian Bone Marrow Cytogenetic Test - Chromosomal Analysis
  476 In vitro Mammalian Cell Gene Mutation Test
4.    ECOTOXICITY
  201 Alga, Growth Inhibition Test
  202 a Daphnia sp., Acute Immobilization Test
  203 Fish, Acute Toxicity Test
  205 Avian Dietary Toxicity Test
  206 Avian Reproduction Test
  207 Earthworm, Acute Toxicity Tests
  213 Honey bee, oral toxicity
  214 Honey bee, contact toxicity
  OPPTS Toxicity to birds (Acute Oral – Japanese quail)
    Avian Acute Oral Toxicity Test
    Other test as customers requirement

Phy&Chem 物化性质实验
  TEST METHOD TEST
  OPPTS Physical State
  OPPTS Color.
  OPPTS Odor
  OECD 102 Melting Point
    Boling Point: (Liquids at room temperature:) OECD 103.
  OECD 109- CIPAC MT3 Density: OECD 109- CIPAC MT 3/ MT 58.4.
  OECD 104 Vapor pressure: OECD 104.ã
  Not offered presently Volatility. ã
    Solubility in Water: OECD 105; CIPAC MT 157.1 y 157.2. ã (at single pH)
    Absorption Spectrums of active ingredient. * Two of:
2.7.1       IR (infra red) and/or
2.7.2       NMR (Nuclear Magnectic Resonance) or
2.7.3     MS (Mass Spectophotometry)
  OECD 105 Solubilidad en solventes orgánicos
  OECD 107, OECD 117 N-octanol/water coefficient partition:OECD117, FIFRA63-11. ã
    Stability in Water: OECD 111. ã
  CIPAC MT 12 Flammability: Flash Point: CIPAC MT 12.
  OECD 115; EEC A5 Superficial tension: OECD 115 EEC A5.
    Explosive properties: EEC A. 14; FIFRA 63-16ã
  FIFRA 63-20 Oxydizing properties: (corrosivity).- EEC A17; FIFRA 63-20.
  FIFRA 63-20 Reactivity with packaging material: FIFRA 63-20.
  CIPAC MT75; FIFRA  63-12 pH: CIPAC MT 75; FIFRA 63-12.
    Water dissociation constant: OECD 112; FIFRA 63-10. ã
  CIPAC MT 22. Viscosidad: (para sustancias líquidas). CIPAC MT 22.
    Other test as customers requirement



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